Category IV: Supporting evidence from only in vitro human experiments
Number of EDCs: 339
Chemical nameChemical identifierLiterature identifier
ChlorocresolDED000026PMID:9828346
AmpyroneDED000030PMID:29289696
AnastrozoleDED000032PMID:12153753
CitalopramDED000038PMID:26162595, PMID:28179152
DanthronDED000041PMID:11459643
EconazoleDED000047PMID:20708073
EmodinDED000048PMID:11459643
Rac-[6]-GingerolDED000053PMID:23590819
IndomethacinDED000059PMID:23670170
1-Methyl-3-isobutylxanthineDED000060PMID:12127262
LetrozoleDED000064PMID:20087668
MitotaneDED000068PMID:28531659, PMID:9168009
PatulinDED000070PMID:24995434
PhenolsulfonphthaleinDED000072PMID:17235438
PhenothrinDED000073PMID:10064545, PMID:15118252
PropazineDED000077PMID:10746939, PMID:27431321
SulfathiazoleDED000081PMID:20630653
TrichlorfonDED000089PMID:17329077
CycloheximideDED000100PMID:7662587
1,2-Dihydroxy-9,10-anthracenedioneDED000103PMID:11459643
Acetyl tributyl citrateDED000114PMID:28235592, PMID:35567983
Tri-p-cresyl phosphateDED000116PMID:22446829, PMID:32559878, PMID:35135005, PMID:37522340
Tri(2-butoxyethyl) phosphateDED000117PMID:22446829, PMID:37522340
p-tert-AmylphenolDED000122PMID:8593856
2,6-DihydroxyanthraquinoneDED000125PMID:11459643
Butyl glycolyl butyl phthalateDED000131PMID:12686300
2-Phenyl phenolDED000137PMID:12737316
4-sec-ButylphenolDED000148PMID:8593856
Terephthalic acidDED000151PMID:26289545
1,4-CyclohexanedimethanolDED000159PMID:26289545
2,2,2-TrichloroethanolDED000176PMID:29294279
DicofolDED000177PMID:15253041, PMID:34164426
Chrysophanic acidDED000197PMID:11459643
Perfluorooctyl iodideDED000198PMID:21990342, PMID:25871633
NoramidopyrineDED000200PMID:29289696
FormestaneDED000207PMID:12153753, PMID:33098425
alpha-NaphthoflavoneDED000209PMID:20823264
4-Ethyl-1-phospha-2,6,7 trioxabicyclo(2.2.2)octane-1-oxideDED000223PMID:28430429
p-ChlorostyreneDED000225PMID:19654042
4-Chloro-2-cresolDED000229PMID:9828346
m-ChlorostyreneDED000230PMID:19654042
o-ChlorostyreneDED000231PMID:19654042
2,4,2',4'-TetranitrobiphenylDED000237PMID:28430429
t-Butyl hydroquinoneDED000242PMID:29236469
Ethyl p-nitrophenyl benzenethiophosphonateDED000244PMID:15253041
Tripropyltin chlorideDED000246PMID:25465476
1,2,5,6,9,10-HexabromocyclododecaneDED000252PMID:15585367
1,2-Dibromo-4-(1,2-dibromoethyl)cyclohexaneDED000255PMID:20049203
TerbuthylazineDED000262PMID:27431321
Cadmium nitrateDED000274PMID:20197112
Tri-(2-chloroisopropyl)phosphateDED000277PMID:22446829, PMID:37522340
Tetradecanoylphorbol acetateDED000284PMID:15187238, PMID:15884376, PMID:35940389
Tris(2,3-dibromo-1-propyl) phosphateDED000292PMID:28430429
Tributyl phosphateDED000293PMID:26979758
8-Bromo cyclic adenosine monophosphateDED000294PMID:11675267, PMID:15187238, PMID:15884376, PMID:33984659
2,6-DichlorostyreneDED000298PMID:19654042
2,3,3',4',6-PentachlorobiphenylDED000312PMID:16216300, PMID:24675366
2,3,6,2',3',6'-HexachlorobiphenylDED000315PMID:29124635
2,2',3,5'-TetrachlorobiphenylDED000323PMID:24675366
2,2',4,5'-TetrachlorobiphenylDED000324PMID:24675366
IsoprothiolaneDED000326PMID:17904202
DeoxynivalenolDED000329PMID:22982764, PMID:35588983
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxideDED000333PMID:29144987, PMID:34050522, PMID:37167865, PMID:37802009
TriadimenolDED000334PMID:15253041, PMID:39365753
1,2,7,8-TetrachlorodibenzofuranDED000338PMID:1332906
Octyl dimethyl 4-aminobenzoic acidDED000339PMID:11333184
ParoxetineDED000343PMID:26162595, PMID:28179152
FlutolanilDED000344PMID:17904202
Dibenzofuran, 2,3,7,8-tetrabromo-DED000346PMID:17447562
LovastatinDED000348PMID:15884376
MifepristoneDED000350PMID:22414680
2,4,4',6-TetrachlorobiphenylDED000356PMID:8593856
6-HydroxyflavoneDED000367PMID:18626888
2,2-Bis(4-hydroxyphenyl)-1,1,1-trichloroethaneDED000371PMID:22549810
4,4'-DiiodobiphenylDED000372PMID:15585367
2,2-di(4-Methacryloxyphenyl)propaneDED000373PMID:18174953, PMID:8919768, PMID:9449681
1,3,5-Tribromo-2-(prop-2-en-1-yloxy)benzeneDED000374PMID:25454221
2-(Propan-2-yl)-9H-thioxanthen-9-oneDED000376PMID:23208609, PMID:26692070
FludioxonilDED000383PMID:23052036, PMID:31927052, PMID:39201710
PenfenateDED000385PMID:22119440
7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthaleneDED000386PMID:23084589
BAY 93820DED000387PMID:20688129
2,2-Dimethoxy-2-phenylacetophenoneDED000388PMID:26692070
PenconazoleDED000394PMID:23811263
3,3',4,4'-TetrabromobiphenylDED000406PMID:17447562
1,2-Diphenylcyclobutane, cis-DED000412PMID:11485868
Bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalateDED000417PMID:24064184
2,4-Diethyl-9H-thioxanthen-9-oneDED000423PMID:23208609
EscitalopramDED000425PMID:28179152
4-Isopropyl-9H-thioxanthen-9-oneDED000428PMID:23208609
Enniatin BDED000430PMID:25625232
FenhexamidDED000433PMID:23052036, PMID:33484789, PMID:35780843
LilialDED000436PMID:19338011
2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroetheneDED000437PMID:16243481
Cyclooctane, 1,2,5,6-tetrabromo-DED000439PMID:24064184
Tributyltin bromideDED000440PMID:16513093
NaringeninDED000443PMID:12153753, PMID:24586459
PulmatinDED000445PMID:11459643
EthylketocyclazocineDED000447PMID:9831078
EtorphineDED000455PMID:9831078
3,3-dibromobisphenol ADED000456PMID:11693576
3-monobromobisphenol ADED000457PMID:11693576
2,2-bis(4-hydroxyphenyl)-propanolDED000458PMID:9449681
EtomidateDED000459PMID:18626888
DieldrinDED000461PMID:17848404, PMID:7925178
3,3-bis(4-hydroxyphenyl)pentaneDED000462PMID:9449681
Bis(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,12-heneicosafluoro-1-dodecanol) hydrogen phosphateDED000469PMID:23142464
3,5-Dibromo-2-(2,4-dibromophenoxy)phenolDED000477PMID:16177243, PMID:18022659, PMID:20549613
4,4'-Propane-1,1-diyldiphenolDED000480PMID:9449681
Biochanin ADED000483PMID:12153753, PMID:36555195
FormononetinDED000484PMID:12153753
LuteolinDED000485PMID:23836117
BudesonideDED000486PMID:23616146
3-MethylquercetinDED000488PMID:14706564
CyproteroneDED000499PMID:17822730
LevetiracetamDED000500PMID:19566492, PMID:20726872
FluvoxamineDED000503PMID:26162595, PMID:28179152
AlternariolDED000505PMID:23665424, PMID:37298472, PMID:37683805, PMID:39262136
CyhexatinDED000511PMID:25465476
Alpha-EndosulfanDED000512PMID:7925178, PMID:8593856
beta-ZearalenolDED000514PMID:21803136
lambda-CyhalothrinDED000516PMID:18419197, PMID:20097460, PMID:26877835
1H-Benzimidazole, 5-methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2- pyridinyl)methyl)sulfinyl)-DED000519PMID:27002602
Omeprazole, (R)-DED000520PMID:27002602
3'-Methoxy-4'-nitroflavoneDED000523PMID:20823264
2-(Perfluorooctyl)ethyl dihydrogen phosphateDED000524PMID:23142464
1,2,3-Tribromo-5-(2,4-dibromophenoxy)-4-methoxybenzeneDED000527PMID:18313098
4,4-bis(4-hydroxyphenyl)heptaneDED000531PMID:9449681
1,2-Diphenylcyclobutane, trans-DED000532PMID:11485868
2-OH-BDE-123DED000534PMID:18313098
Endosulfan IIDED000535PMID:33433340, PMID:7925178
AldrinDED000536PMID:16996190, PMID:35887249, PMID:37092452
2-Bromoallyl 2,4,6-tribromophenyl etherDED000538PMID:25454221
6-MeO-BDE-47DED000546PMID:20549613
Ascorbic acidDED000555PMID:23590819
ChlortetracyclineDED000556PMID:20630653
OxytetracyclineDED000557PMID:20630653
2-EthylhexyltetrabromobenzoateDED000558PMID:24064184, PMID:34875267
3,3',4,5'-Tetrabromodiphenyl etherDED000559PMID:18313098
MonophenyltinDED000566PMID:25465476
MiconazoleDED000589PMID:20708073, PMID:31330226
2,4,6-TrichlorophenolDED000600PMID:21296122, PMID:30609499
Butylated hydroxytolueneDED000637PMID:29236469, PMID:31310931
Perfluoro-1-iodohexaneDED000646PMID:21990342, PMID:29665550
4,4'-Isopropylidenedi-2,6-xylolDED000652PMID:28616630, PMID:31388671, PMID:32387340
2,3-Dibromopropyl 2,4,6-tribromophenyl etherDED000658PMID:25454221, PMID:29556062
alpha-ZearalenolDED000676PMID:21803136, PMID:27401186, PMID:30189007, PMID:39262136
FluconazoleDED000691PMID:31330226
LamotrigineDED000692PMID:29718108, PMID:37505509
DibutylstannaneDED000697PMID:29549738, PMID:30045567
Benzyl p-hydroxybenzoateDED000698PMID:31388671, PMID:35810903
3,4-DichloroanilineDED000699PMID:31100596, PMID:38000554
N-MethyldiethanolamineDED000705PMID:31310931
DiolamineDED000711PMID:31310931
CaptanDED000715PMID:29953993
FolpetDED000716PMID:29953993
1-NaphthylamineDED000717PMID:31100596
1-Aminomethylphosphonic acidDED000721PMID:31295307
3,3'-DichlorobiphenylDED000724PMID:29518658
CaptafolDED000725PMID:29953993
2,2'-DichlorobiphenylDED000729PMID:29518658
NapropamideDED000731PMID:31524045
2,4'-DichlorobiphenylDED000734PMID:29518658
Diclofop-methylDED000736PMID:31524045
Mono-n-butyltinDED000737PMID:29549738
1,6-DiiodoperfluorohexaneDED000744PMID:29665550
2,4'-Dihydroxydiphenyl sulfoneDED000745PMID:31388671
1,1-Bis(4-hydroxyphenyl)-2,2-dichloroethyleneDED000747PMID:31388671
HydroxyflutamideDED000748PMID:29556062
theta-CypermethrinDED000749PMID:30611075
Alpha-CypermethrinDED000751PMID:30611075
Phenol, 4-((4-(phenylmethoxy)phenyl)sulfonyl)-DED000754PMID:31388671
Mono(2-ethyl-5-oxohexyl)phthalateDED000755PMID:30847963
2-Ethyl-5-carboxypentyl phthalateDED000756PMID:30847963
Mono(2-ethylhexyl) terephthalateDED000757PMID:30847963
NaproxenDED000758PMID:29655108
Propanoic acid, 2-(4-(2,4-dichlorophenoxy)phenoxy)-, methyl ester, (2S)-DED000759PMID:31524045
PropisochlorDED000760PMID:31524045
Mono(2-ethyl-5-hydroxyhexyl) phthalateDED000761PMID:30847963, PMID:36375056, PMID:38992643
Bisphenol PDED000767PMID:31388671
(1S)-cis-(alphaR)-cypermethrinDED000769PMID:30611075
3-[(3-(2-Carboxyethyl)-4-methylpyrrol-2-YL)methylene]-2-indolinoneDED000773PMID:31734698
PhtppDED000779PMID:29495557
(1S)-trans-(Alphar)-cypermethrinDED000782PMID:30611075
(S)-LactofenDED000783PMID:31524045
Napropamide-MDED000784PMID:31524045
N-(6-Aminopyridin-2-yl)-4'-cyanobiphenyl-4-sulfonamideDED000787PMID:30021644
(R)-LactofenDED000789PMID:31524045
4-Hydroxybenzoic acid 3-hydroxybutyl esterDED000792PMID:29945225
CatecholDED000794PMID:36241036, PMID:39512757
Chloroacetic AcidDED000795PMID:36963690
O-CresolDED000796PMID:39512757
3-MethylcatecholDED000797PMID:39512757
Hydrogen PeroxideDED000798PMID:34202188
HydroquinoneDED000799PMID:36241036
AlprazolamDED000804PMID:32991989
CarbamazepineDED000805PMID:37505509
Carbonyl cyanide (m-chlorophenyl)hydrazoneDED000806PMID:35940389
DiazepamDED000808PMID:32991989
DibenzothiopheneDED000809PMID:33314207
2,5-Dihydroxybenzoic acidDED000811PMID:36241036
1H-Pyrrole-1-carboxamide, 3-ethyl-2,5-dihydro-4-methyl-N-2-4-(trans-4-methylcyclohexyl)aminocarbonylaminosulfonylphenylethyl-2-oxo-DED000812PMID:33002602
6-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)cyclopropyl)-3-pyridinecarboxylic acidDED000814PMID:36750942
MetforminDED000815PMID:33002602
Methyl SalicylateDED000817PMID:39454092
OxazepamDED000819PMID:32991989
4-ChlorophenolDED000820PMID:36241036
PentoxifyllineDED000822PMID:33984659
Mitomycin CDED000826PMID:37298413
2-AminophenolDED000827PMID:39512757
Bromoacetic AcidDED000829PMID:36963690
Tribromoacetic AcidDED000831PMID:36963690
1,1',1''-(Chlorosilylidyne)tris(benzene)DED000832PMID:31927052
o-Cresyl phosphateDED000833PMID:32234386, PMID:32559878
RotenoneDED000835PMID:38802024
Diphenyl phthalateDED000836PMID:34697989, PMID:38423186
CarbazoleDED000837PMID:32344252
Isobutyl salicylateDED000838PMID:39454092
Isoamyl salicylateDED000839PMID:39454092
HexabromobenzeneDED000840PMID:34875267
PentabromotolueneDED000841PMID:34875267
VeratroleDED000842PMID:39512757
MethyleugenolDED000843PMID:39512757
2-Methoxy-4-MethylphenolDED000844PMID:39512757
2-BromophenolDED000845PMID:36241036
2,4-Di-tert-butylphenolDED000846PMID:36750942
DichloneDED000848PMID:36470526
di-N-Octyl PhthalateDED000850PMID:36115423
2-Ethylhexyl salicylateDED000851PMID:39454092
Ethyl SalicylateDED000852PMID:39454092
ChloranilDED000853PMID:38555059
AzacytidineDED000858PMID:39330587
Tri-m-cresyl phosphateDED000861PMID:32559878
Isopropyl salicylateDED000863PMID:39454092
PentabromophenolDED000864PMID:36241036
3-MethoxycatecholDED000867PMID:39512757
4,4'-Dihydroxydiphenyl etherDED000870PMID:32007685, PMID:37816402
TetrahydrocannabinolDED000871PMID:37430350
4-ChlorocatecholDED000872PMID:39512757
3-IsopropylcatecholDED000873PMID:39512757
Urea, (3,4-dichlorophenyl)-DED000874PMID:38000554
4-HexylphenolDED000875PMID:38997027
Trioctyl trimellitateDED000876PMID:33628236
4,5-DichlorocatecholDED000877PMID:39512757
DeethylatrazineDED000880PMID:39365753
Nickel DichlorideDED000886PMID:32901497
Lead chlorideDED000887PMID:32004626
Copper sulfate pentahydrateDED000888PMID:32004626, PMID:32437254
3,5-DichlorocatecholDED000889PMID:39512757
6-Chloro-2,3-dihydrobenzoxazol-2-oneDED000892PMID:32007685
Monobenzyl phthalateDED000895PMID:35567983
Pcb 74DED000896PMID:39136868
Pcb 138DED000897PMID:39136868
Pcb 170DED000899PMID:36060944
ClimbazoleDED000900PMID:38795739
Pcb 99DED000901PMID:39136868
2,2',3,3',5,6'-HexachlorobiphenylDED000903PMID:35887249
StaurosporineDED000904PMID:35940389
4-EthylguaiacolDED000905PMID:39512757
Perfluorohexanoic AcidDED000907PMID:32348926, PMID:35696490, PMID:37052835, PMID:38728818
Perfluorodecanesulfonic acidDED000908PMID:35696490, PMID:36878351
3-FluorocatecholDED000909PMID:39512757
Perfluoroheptanesulfonic acidDED000911PMID:36878351
Perfluorotetradecanoic acidDED000912PMID:36122607, PMID:36878351
Propyl salicylateDED000913PMID:39454092
4-Ethyl-1,2-benzenediolDED000916PMID:39512757
Phenol, 4,4'-(1-methylethylidene)bis(2-(2-propen-1-yl)-DED000918PMID:38128231
Tris(isopropylphenyl) phosphateDED000920PMID:35135005, PMID:37522340
RosiglitazoneDED000921PMID:32170302, PMID:33865937, PMID:35101577, PMID:36750942, PMID:38048832, PMID:38802024
4,4'-Methylenebis(2,6-dimethylphenol)DED000922PMID:33866271, PMID:34069744
TetraconazoleDED000923PMID:37852555, PMID:39365753
BexaroteneDED000925PMID:31927052
DifenoconazoleDED000927PMID:37852555, PMID:39365753
MetconazoleDED000928PMID:37852555
CyprodinilDED000929PMID:35853389, PMID:37959855
4,5-Dichloro-2-n-octyl-4-isothiazolin-3-oneDED000931PMID:37939439
PyridabenDED000932PMID:38423186
Bis(2-propylheptyl)phthalateDED000933PMID:35567983
Benzene, 2,4-dimethoxy-1-methyl-DED000935PMID:39512757
N-(3,5-Dichlorophenyl)-2-hydroxy-2-methyl-3-butenamideDED000938PMID:35595151
2-((((3,5-Dichlorophenyl)amino)carbonyl)oxy)-2-methyl-3-butenoic acidDED000939PMID:35595151
4-AminocatecholDED000942PMID:39512757
Bde 153DED000943PMID:39136868
Phosphoric acid, (1,1-dimethylethyl)phenyl diphenyl esterDED000944PMID:35135005
4-Fluoro-1,2-benzenediolDED000945PMID:39512757
Dimethyl phosphorothioateDED000947PMID:32007685
Bis(1,3-dichloro-2-propyl) phosphateDED000949PMID:32150676
CatecholamineDED000950PMID:39512757
BoscalidDED000951PMID:35853389, PMID:37959855
2,2-Bis(4-hydroxy-3-isopropylphenyl)propaneDED000952PMID:32508751, PMID:37816402, PMID:38128231
Bis(4-hydroxyphenyl)diphenylmethaneDED000953PMID:32508751, PMID:37816402
1,3,6,8-TetrabromocarbazoleDED000956PMID:32344252
DithiothreitolDED000957PMID:36122607
ThapsigarginDED000960PMID:35940389
Sophoraflavanone BDED000962PMID:34164426
IsoxanthohumolDED000963PMID:34164426
CannabidiolDED000967PMID:37430350
IsoeugenolDED000969PMID:37819454
CotinineDED000970PMID:38453095
Stf-31DED000971PMID:34311058
9-(nonafluorobutyl)-2,3,6,7-tetrahydro-1H,5H,11H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-11-oneDED000973PMID:35093747
Propanoic acid, 2-(4-hydroxyphenoxy)-, ethyl esterDED000978PMID:32007685
Perfluorotridecanoic acidDED000979PMID:36122607, PMID:36878351
Oxine-copperDED000980PMID:36470526
4-NitrocatecholDED000983PMID:39512757
4,4'-(3,3,5-Trimethylcyclohexylidene)bis(phenol)DED000988PMID:39520287
2-(Heptafluoropropyl)-3-phenylquinoxalineDED000989PMID:35093747
SitagliptinDED000990PMID:33002602
PerfluorooctanoateDED000991PMID:37148752
MetofluthrinDED000992PMID:35853389
FlumethrinDED000996PMID:34142587
2,4,7-TrimethyldibenzothiopheneDED000998PMID:33314207
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oximeDED001001PMID:39341470
(6R,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-25-methylmilbemycin BDED001002PMID:35853389
Milbemycin A4DED001003PMID:35853389
CyflumetofenDED001006PMID:36933840
2,4,4'-Tribromodiphenyl etherDED001010PMID:35887249
Npc328442DED001012PMID:39136868
N-(3,4-Dichlorophenyl)-N'-methoxyureaDED001013PMID:38000554
2,2-Bis(2-hydroxy-5-biphenylyl)propaneDED001015PMID:38128231
Diiodoacetic acidDED001017PMID:36963690
1,2,9,10-TetrachlorodecaneDED001018PMID:38331103
EnzalutamideDED001019PMID:35093747
Mono-3-hydroxybutyl phthalateDED001020PMID:35567983
2-(3-Chloro-4-hydroxyphenyl)-2-(4-hydroxyphenyl)propaneDED001021PMID:38128231
Trichlorobisphenol ADED001022PMID:38128231
1,2-DichlorotetradecaneDED001023PMID:38331103
Chloro(iodo)acetic acidDED001025PMID:36963690
Potassium hexafluorophosphateDED001028PMID:37094483
Bisphenol A monosulfateDED001031PMID:35041905
2-(1-Phenoxypropan-2-yloxy)pyridineDED001032PMID:32007685
2-[(Dimethoxyphosphoryl)sulfanyl]butanedioic acidDED001033PMID:32007685
2-[(2-Hydroxy-2-methylpropoxy)carbonyl]benzoateDED001034PMID:35567983
2-(1-Hydroxy-7-methyloctoxy)carbonylbenzoateDED001035PMID:35567983
Bis(2-chloro-1-methylethyl) hydrogen phosphateDED001038PMID:32150676
Monocarboxy isononyl phthalateDED001039PMID:35567983
2-(6-Hydroxy-2-propylheptoxy)carbonylbenzoic acidDED001040PMID:35567983
1,2-Cyclohexanedicarboxylic Acid Mono 4-Methyloctyl EsterDED001042PMID:35567983
Difluoro{[2,2,4,5-tetrafluoro-5-(trifluoromethoxy)-1,3-dioxolan-4-yl]oxy}acetic acidDED001043PMID:37052835, PMID:38728818
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.